Abstract Background Amyotrophic lateral sclerosis is a fatal neuromuscular disorder characterized by progressive death of the upper and lower motor neurons in the central nervous system.Patients with this disease die mostly as a result of respiratory failure; however, owing to prolonged survival through assisted ventilation, cardiovascular causes a

With the advent of single B-cell cloning technology, we can isolate antibodies against virtually any antigen to study the interaction of a given pathogen with the immune system and develop novel therapeutic strategies.Antibodies directed against the capsid of adeno-associated viruses (AAV) are a significant obstacle to effectively leveraging AAV as

The seismoelectric phenomenon associated with propagation of seismic waves in fluid-saturated porous media has been studied for many decades.The method has a great potential to monitor subsurface fluid saturation changes associated with production of hydrocarbons.Frequency of the seismic source has a significant impact on measurement of the seismoe